Every year tens of thousands of new pieces of legislation are proposed, thousands of which are passed into law. These laws can affect businesses in many ways, but there is no easy way for businesses to find and track legislation that will directly affect them.
I suggest using OpenStates.org's free API to gather data about legislation in different states and then build statistical or machine-learning based models that can predict the likelihood that new pieces of legislation will pass. Legislative tracking is already a hundred million dollar industry, but there is no company yet doing predictive analysis at the state level. Business consulting firms would be a huge target demographic for this business.